What Happens When Men are Given Female Hormones?


Introduction: Hormones play a crucial role in the functioning of our bodies, influencing various physiological processes. While hormones are typically associated with a specific gender, both men and women produce a combination of male and female hormones. In certain cases, medical professionals may prescribe female hormones to men for various reasons. This article explores the effects and implications of introducing female hormones into a male body.

Hormones and Gender

1.1 Understanding Hormones: Hormones are chemical messengers that regulate bodily functions and play a key role in development, growth, and reproduction.

1.2 Male Hormones: Testosterone is the primary male hormone, responsible for the development of male characteristics such as facial hair, deep voice, and muscle mass.

1.3 Female Hormones: Estrogen and progesterone are the main female hormones, involved in the development of secondary sexual characteristics like breast growth, menstrual cycles, and maintenance of pregnancy.

Reasons for Administering Female Hormones to Men

2.1 Gender Transition: Some transgender individuals assigned male at birth may choose to undergo hormone replacement therapy (HRT) to align their physical appearance with their gender identity.

2.2 Hormone Imbalance: In certain medical conditions, men may have imbalances in their hormone levels, requiring the administration of female hormones to restore balance.

2.3 Prostate Cancer Treatment: Female hormones are sometimes used in the treatment of advanced prostate cancer, as they can suppress the production of testosterone, which fuels the growth of cancer cells.

Feminizing Hormone Therapy at Seattle Children’s

Effects of Female Hormones on Men

3.1 Physical Changes: The introduction of female hormones can result in various physical changes, including breast development, softer skin, decreased body hair growth, and potentially a redistribution of body fat.

3.2 Emotional and Psychological Effects: Hormones can also influence mood and emotions. Some men may experience changes in their emotional state, including increased sensitivity or changes in libido.

3.3 Infertility and Reproductive Function: Female hormones can suppress the production of sperm and affect fertility. Men considering hormone therapy should discuss their reproductive goals with a healthcare professional.

Risks and Side Effects

4.1 Blood Clotting: Estrogen, a key female hormone, may increase the risk of blood clot formation, which can lead to serious health complications such as deep vein thrombosis or pulmonary embolism.

4.2 Cardiovascular Health: Hormone imbalances can impact cardiovascular health. Men with pre-existing heart conditions should be closely monitored when undergoing hormone therapy.

4.3 Bone Density: Estrogen plays a role in maintaining bone density. The use of female hormones in men may affect bone health and increase the risk of osteoporosis.

4.4 Liver Function: Hormone therapy can potentially impact liver function and should be closely monitored in individuals with liver disease or a history of liver problems.

Long-Term Effects and Considerations

5.1 Monitoring and Regular Check-ups: Regular monitoring of hormone levels and overall health is essential for individuals undergoing hormone therapy to identify any potential complications or adjustments needed.

5.2 Reversible and Irreversible Effects: Some effects of female hormones may be reversible upon discontinuation of therapy, while others, such as breast development, may be permanent.

5.3 Individual Variations: The effects of female hormones on men can vary based on individual factors such as genetics, dosage, duration of therapy, and overall health.

Frequently Asked Questions

FAQ 1: Will taking female hormones make a man become a woman?

No, taking female hormones alone will not change a person’s gender identity. Hormone therapy may help align physical characteristics with gender identity but does not determine one’s gender.

FAQ 2: Can men experience menstrual cycles when taking female hormones?

No, men cannot experience menstrual cycles as they do not have a uterus. Female hormones may impact certain aspects of reproductive function, but menstruation is not one of them.

FAQ 3: Is hormone therapy reversible?

Some effects of hormone therapy may be reversible upon discontinuation, such as changes in mood or libido. However, certain physical changes, like breast development, may be permanent.

FAQ 4: Are there any age restrictions for hormone therapy in men?

There are no strict age restrictions for hormone therapy in men. However, healthcare professionals consider individual health factors and overall well-being when determining the suitability of hormone therapy.

FAQ 5: Can men taking female hormones still father children?

The use of female hormones can suppress sperm production, making it difficult to conceive. Men interested in preserving their fertility should discuss options such as sperm banking before starting hormone therapy.

FAQ 6: Are there any alternatives to hormone therapy for gender transition?

Yes, hormone therapy is just one aspect of gender transition. Other options include surgical interventions, voice therapy, and social support networks. Each individual’s journey is unique, and healthcare professionals can provide guidance on available alternatives.


In conclusion, the introduction of female hormones into a male body can result in various physical, emotional, and psychological changes. Whether for gender transition, hormone imbalance, or prostate cancer treatment, hormone therapy should be carefully supervised by healthcare professionals. Understanding the potential risks, side effects, and long-term considerations is crucial for individuals undergoing this treatment. Open communication with healthcare providers and support networks is essential to ensure the best possible outcomes for those choosing hormone therapy.

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